abstract：:The apparent Mn2+ binding constant for L-alpha-dipalmitoylphosphatidylcholine (DPPC) bilayers dispersed in monovalent salt and MnCl2 dispersions was determined as a function temperature using electron paramagnetic resonance (ERP). Reproducibility in the data sets requires the use of a standard salt solution and dual c...

journal_title：Chemistry and physics of lipids

authors： Cunningham BA,Gelerinter E,Lis LJ

更新日期：1988-03-01 00:00:00

abstract：:In X-ray diffraction studies of hydrated (greater than 60%) cholesterol/dioleoylphosphatidylcholine mixtures the lipid packing band showed an abrupt transition from liquid crystal-type to gel-type position and definition at a temperature which decreased progressively to almost -50 degrees C as the proportion of choles...

journal_title：Chemistry and physics of lipids

authors： Finean JB,Hutchinson AL

更新日期：1988-01-01 00:00:00

abstract：:The stimulatory, cytostatic and cytotoxic effects of polyunsaturated fatty acids, prostaglandins, thromboxanes, hydroperoxy fatty acids, hydroxy fatty acids and leukotrienes on normal and tumor cells are described. Their effects are related to the ability of the cells to undergo lipid peroxidation. The significance of...

journal_title：Chemistry and physics of lipids

authors： Bégin ME

更新日期：1987-11-01 00:00:00

abstract：:The in vitro effect of apolipoprotein C-II (apo C-II) on the apolipoprotein C-III (apo C-III) induced activation of bovine milk lipoprotein lipase (LPL) was studied in vitro using a synthetic substrate. Apo C-III effectively inhibited, in a dose-dependent manner, the activation of lipoprotein lipase induced by apo C-I...

journal_title：Chemistry and physics of lipids

authors： Catapano AL

更新日期：1987-10-01 00:00:00

abstract：:Iron is required for the initiation of lipid peroxidation. Evidence is presented that lipid peroxidation requires both Fe3+ and Fe2+, perhaps with oxygen to form a Fe3+-dioxygen-Fe2+ complex. Other mechanisms of initiation, mostly involving the iron-catalyzed formation of hydroxyl radical, are described and discussed ...

journal_title：Chemistry and physics of lipids

authors： Minotti G,Aust SD

更新日期：1987-07-01 00:00:00

abstract：:Age-related fluorescent and cross-linked proteins increase with lipid oxidation of tissues. The fluorophores and cross-links have been considered to be conjugated Schiff bases between amino groups of proteins and malonaldehyde. Our recent studies showed that the fluorophores produced in the in vitro reaction of protei...

journal_title：Chemistry and physics of lipids

authors： Kikugawa K,Beppu M

更新日期：1987-07-01 00:00:00

abstract：:The work presented here demonstrates that the phenomenon of spontaneous vesiculation is not restricted to charged lipids and lipid mixtures, but occurs also in isoelectric phospholipid mixtures consisting of egg phosphatidylcholine (EPC) and egg lysophosphatidylcholine (lyso-EPC). 1H high-resolution NMR and freeze-fra...

journal_title：Chemistry and physics of lipids

authors： Hauser H

更新日期：1987-05-01 00:00:00

abstract：:Inverted cubic and isotropic phases have been observed in phospholipid and glycolipid systems. These phases exhibit characteristic morphologies in freeze-fracture electron micrographs, isotropic 31P-NMR resonances and (in some cases) cubic X-ray diffraction patterns. It is proposed here that these phases may form from...

journal_title：Chemistry and physics of lipids

authors： Siegel DP

更新日期：1986-12-31 00:00:00

abstract：:A polymorphic variation of sialic acid species of sialosyllactosylceramide was found in dog erythrocytes. The analysis of the glycolipids in the erythrocytes of the individual dogs in a family of a Japanese breed of dog, Shiba-Inu, showed that the expression of sialosyllactosylceramide containing N-glycolylneuraminic ...

journal_title：Chemistry and physics of lipids

authors： Yamakawa T,Suzuki A,Hashimoto Y

更新日期：1986-12-15 00:00:00

abstract：:The oligosaccharide chain of glycosphingolipids (GSLs) has a marked influence on their thermotropic behavior, intermolecular packing and surface electrical potential. The transition temperature and enthalpy of GSLs decrease proportionally to the complexity of the polar head group and show a linear dependence with the ...

journal_title：Chemistry and physics of lipids

authors： Maggio B,Fidelio GD,Cumar FA,Yu RK

更新日期：1986-12-15 00:00:00

abstract：:The effects of Ca2+ on rotational and translational diffusion of lipids in multilamellar dimyristoylphosphatidylcholine (DMPC)-water systems were investigated by time-resolved phosphorescence anisotropy steady-state fluorescence polarization and fluorescence recovery after photobleaching (FRAP) experiments. Above the ...

journal_title：Chemistry and physics of lipids

authors： Blatt E,Vaz WL

更新日期：1986-10-01 00:00:00

abstract：:Fourier Transform Infra-red and Raman Spectroscopies indicate that 7 alpha-hydroxycholesterol and 7-ketocholesterol have a diminished capacity to condense (increase the packing order of) fluid-state dipalmitoylphosphatidylcholine (DPPC) acyl chains when compared with the effects of cholesterol and the other oxidized s...

journal_title：Chemistry and physics of lipids

authors： Rooney M,Tamura-Lis W,Lis LJ,Yachnin S,Kucuk O,Kauffman JW

更新日期：1986-08-01 00:00:00

abstract：:The interactions of liposomes with cells have been extensively studied to determine their potential use as vehicles for the delivery of drugs in vivo. Since intravenously administered liposomes are, for the most part, cleared by cells of the reticuloendothelial system (RES), considerable effort has been made to take a...

journal_title：Chemistry and physics of lipids

authors： Schroit AJ,Madsen J,Nayar R

更新日期：1986-06-01 00:00:00

abstract：:The reasons for lipid diversity in membranes are not understood. Here we review evidence supporting the proposal that factors related to the polymorphic capabilities of lipids provide a rationale for lipid diversity. In particular, the ability of lipids to adopt different polymorphic phases appears to be related to a ...

journal_title：Chemistry and physics of lipids

authors： Cullis PR,Hope MJ,Tilcock CP

更新日期：1986-06-01 00:00:00

abstract：:The ionic transport properties, capacitance and breakdown voltage of bilayer macrovesicles made from lecithin, dodecaprenol and their mixtures have been studied. The electrical measurements showed that polyprenol in lipid bilayers increases membrane permeability and elasticity, and decreases membrane thickness. Some p...

journal_title：Chemistry and physics of lipids

authors： Janas T,Kuczera J,Chojnacki T,Krajewska-Rychlik I

更新日期：1986-03-01 00:00:00

abstract：:A simplified procedure for lipid digestion, well suited for handling a large number of samples, was used to analyze a variety of common phospholipids. This procedure involves digestion of phospholipids in perchloric acid at 130 degrees C with minimal sample manipulation. For all lipids tested, complete destruction, ne...

journal_title：Chemistry and physics of lipids

authors： Mrsny RJ,Volwerk JJ,Griffith OH

更新日期：1986-01-01 00:00:00

abstract：:The permeability of liposomes to water, glucose, Ca2+ and alkaline cations was monitored by recording the change in absorbance at 450 nm using a rapid reaction stopped-flow spectrophotometer. Liposomes were prepared with egg phosphatidylcholine and concentrations of dolichol ranging from 0.1% to 9% (w/w). Net permeabi...

journal_title：Chemistry and physics of lipids

authors： Boscoboinik DO,Feliz M,Disalvo EA,Belocopitow E

更新日期：1985-11-01 00:00:00

abstract：:A binding protein is described for certain oxygenated derivatives of cholesterol which suppress 3-hydroxy-3-methylglutaryl coenzyme A reductase and cholesterol synthesis in cultured mammalian cells. This protein is found in the cytosolic fraction of many cell types and is distinct from cytosolic proteins which bind ch...

journal_title：Chemistry and physics of lipids

authors： Taylor FR,Kandutsch AA

更新日期：1985-08-30 00:00:00

abstract：:Structural analysis, a purification scheme and stability information on a fluorescent cholesterol analogue, which has been used as a probe in several model and biological systems, are presented. The proposed structure for the fluorophore, cholestatrien-3 beta-ol, closely resembles that of cholesterol. However, problem...

journal_title：Chemistry and physics of lipids

authors： Fischer RT,Stephenson FA,Shafiee A,Schroeder F

更新日期：1984-11-01 00:00:00

abstract：:The interaction of monovalent cations and membrane phospholipids has a great theoretical and practical importance. Because of the very low differences between the binding forces of monovalent cations to phospholipids, the methods applied up till now did not succeed in completely elucidating this interaction. We develo...

journal_title：Chemistry and physics of lipids

authors： Cserháti T,Szögyi M

更新日期：1983-12-01 00:00:00

abstract：:A convenient universal and fast mass spectrometrical method designed for the molecular species analysis of natural lipids is described. In contrast to the commonly employed procedures the method does not require chemical or enzymatic treatment and does not include chromatographic steps. The method relies on the recogn...

journal_title：Chemistry and physics of lipids

authors： Batrakov SG,Sadovskaya VL,Rozynov BV,Bergelson LD

更新日期：1983-11-01 00:00:00

abstract：:Fusion of the single-walled liposomes of egg phosphatidylcholine as induced by the polyisoprenoids such as solanesol, trans-ethyl decaprenoate (EDP), coenzyme Q10, and dolichol has been investigated adopting the fluorescence quenching method. Relative efficiency of the polyisoprenoids employed on the induced fusion of...

journal_title：Chemistry and physics of lipids

authors： Sunamoto J,Iwamoto K,Tezuka T,Kadosaki K,Kondo H

更新日期：1983-08-01 00:00:00

abstract：:The properties of cholesterol in bilayers of egg phosphatidylcholine (PC) were investigated directly by means of 2H-NMR of specifically-deuterated species (C3, C7, C26, C27). Quadrupole splittings were a measure of molecular ordering, and relaxation times T1 and T2e were indicators of rates of motion. The importance o...

journal_title：Chemistry and physics of lipids

authors： Taylor MG,Akiyama T,Saitô H,Smith IC

更新日期：1982-12-01 00:00:00

abstract：:The stereochemistry of fat digestion and absorption was studied by feeding a triacylglycerol analogue to rats with a thoracic duct cannula. The analogue, rac-1,2-dioleoyl-3-S-tetradecyl-3-thioglycerol-S-oxide was chosen since its enantiomers exhibited high rotation in optical rotary dispersion (ORD) and circular dichr...

journal_title：Chemistry and physics of lipids

authors： Akesson B,Michelsen P

更新日期：1981-12-01 00:00:00

abstract：:The chemical syntheses of a number of C27 15-oxygenated sterols and their derivatives have been pursued to permit evaluation of their activity in the inhibition of sterol biosynthesis in animal cells in culture. Described herein are chemical syntheses of 3 alpha-benzoyloxy-5 alpha-cholest-8(14)-en-15-one, 5 alpha-chol...

journal_title：Chemistry and physics of lipids

authors： Schroepfer GJ Jr,Parish EJ,Kandutsch AA

更新日期：1979-11-01 00:00:00

abstract：:A complex mixture of monoacylglycerols, identified as (C30--C36) corynomycoloylglycerols was isolated from the diethyl ether/acetone-soluble lipids of Corynebacterium pseudotuberculosis. ...

journal_title：Chemistry and physics of lipids

authors： Ioneda T,Silva CL

更新日期：1979-09-01 00:00:00

abstract：:Cholesteryl-phosphoryl-choline (CPC), a hybrid between cholesterol and lecithin, is incorporated into sonicated liposomes and erythrocyte membranes similarly to cholesterol. The effect of CPC on lipid microviscosity and degree of order is smaller, but not significantly than that of cholesterol. It is proposed that CPC...

journal_title：Chemistry and physics of lipids

authors： Lyte M,Shinitzky M

更新日期：1979-04-01 00:00:00

abstract：:The melting behavior of members of newly synthesized series of rac-1,2-diglycerides with substituted phenyl groups or a benzyl group on the 3-position was investigated with differential scanning calorimetry (DSC). Solution crystallized samples had single melting temperatures, higher than those of the quenched or annea...

journal_title：Chemistry and physics of lipids

authors： Joseph JT,Hybl A,Flynn JH

更新日期：1978-10-01 00:00:00

abstract：:From 81 of human plasma of blood-group A Lea nonsecretors three different Lea blood-group active ceramide pentasaccharides (a total of 4.65 mg) have been isolated, all revealing glucose, galactose, N-acetylglucosamine and fucose in molar ratios of 1 : 2 : 1 : 1 as determined by gas liquid chromatography. A fourth bloo...

journal_title：Chemistry and physics of lipids

authors： Hanfland P,Kladetzky RG,Egli H

更新日期：1978-09-01 00:00:00

abstract：:The 13C- and 31P-NMR spectra and DSC thermograms of unsonicated dispersions consisting of phospholipids of varying methylation stages of the propanolamine head group were investigated. Methylation of the head group was accompanied by a corresponding reduction in the phase transition temperatures. In the liquid crystal...

journal_title：Chemistry and physics of lipids

authors： Gawrisch K,Arnold K,Rüger HJ,Kertscher P,Nuhn P

更新日期：1977-12-01 00:00:00

abstract：:A structural studies have been performed on new complex glycolipids extracted from hog gastric mucosa by 0.4 M sodium acetate in methanol-chloroform-water, and which were purified to homogeneity by DEAE-Sephadex and Florisil column chromatography and by preparative thin-layer chromatography in three solvent systems. F...

journal_title：Chemistry and physics of lipids

authors： Slomiany BL,Slomiany A

更新日期：1977-09-01 00:00:00

abstract：:The interactions of iodine, iodide and triiodide with phosphatidylcholine multilayers have been investigated in order to find supporting data for conduction mechanisms of iodine-doped bimolecular lipid membranes. On the basis of order-disorder parameters it can be concluded that phospholipid multilayers interact with ...

journal_title：Chemistry and physics of lipids

authors： Loshchilova E,Karvaly B

更新日期：1977-06-01 00:00:00

abstract：:Reduction of 3beta-benzoyloxy-14alpha,15alpha-epoxy-5alpha-cholest-7-ene with either lithium triethylboro-hydride or lithium aluminum hydride (4 molar excess) gave 5-alpha-cholest-8(14)-en-3beta,15alpha-diol in high yield. Reduction of the epoxy ester with lithium triethylborodeuteride or lithium aluminum deuteride (4...

journal_title：Chemistry and physics of lipids

authors： Parish EJ,Schroepfer GJ Jr

更新日期：1977-04-01 00:00:00

abstract：:Ionic properties of didodecanoylphosphatidylglycerol (C12PG), didodecanolyphosphatidyl-l'-propanol (C12PP), di-(12-methyl, 13-methyl)-pentadecanoylphosphatidylglycerols (C15PG) and dihexadecanoylphosphatidylglycerol (C16PG) have been studied at the air-water interface using titration experiments at constant ionic stre...

journal_title：Chemistry and physics of lipids

authors： Sacré MM,Tocanne JF

更新日期：1977-04-01 00:00:00

abstract：:The polymorphic behavior of three series of tris-homoacyl (C14:0, C16:0 and C18:0) cyclopentane-1,2,3-triol analogs of the natural saturated triglycerides has been studied using differential thermal analysis, Fourier transform infrared spectroscopy, and X-ray diffraction. It was found that the triglyceride analogs der...

journal_title：Chemistry and physics of lipids

authors： Greenwald SM,Hancock AJ,Sable HZ,D'Esposito L,Koenig JL

更新日期：1977-03-01 00:00:00

abstract：:A Raman spectroscopic study has been carried out on a number of cholesterols and cholesterol derivatives in the crystalline state, in order to obtaine some empirical correlations between the Raman spectra and structure of each cholesterol form. Although the Raman spectra of the various cholesterols are highly complex ...

journal_title：Chemistry and physics of lipids

authors： Faiman R

更新日期：1977-01-01 00:00:00

abstract：:1-Acyl-2-succinyl glycero-3-phosphorylcholine (GPC) was synthesized and its properties described. Although 1-acyl-2-succinyl GPC is a good substrate for succinate dehydrogenase, experiments on the incorporation of [2,3-14C] succinate into mitochondrial lipids gave no evidence to indicate that it is an intermediate in ...

journal_title：Chemistry and physics of lipids

authors： Brain FH,Davison AN

更新日期：1976-11-01 00:00:00

abstract：:(1) An analysis has been conducted of the lipids present in three obligately anaerobic bacteria isolated from the ovine rumen belonging to the genus Butyrivibrio. Two of these organisms are rich in phospholipase (A1 + A2) activity, and appear to be different strains of the species fibrisolvens. (2) The only N-containi...

journal_title：Chemistry and physics of lipids

authors： Clarke NG,Hazlewood GP,Dawson RM

更新日期：1976-10-01 00:00:00

abstract：:The mass spectra of a number of C-4alpha- and C-4beta-alkylated cholestan-3beta, 5alpha-diols have been found to contain an intense ion at m/e 332. the corresponding 6beta-alkylated (R) cholestan-3beta, 5alpha-diols exhibit an abundant ion at m/e 331 + R. The mass spectra of cholestan-5alpha-ol and cholestan-3beta, 5a...

journal_title：Chemistry and physics of lipids

authors： Knapp FF,Wilson MS,Schroepfer GJ Jr

更新日期：1976-02-01 00:00:00

abstract：:2-N-(Hexadecanoyl)-amino-4-nitrophenyl phosphorylcholine-hydroxide a compound resembling sphingomyelin is synthesized. It is cleaved by sphingomyelinase to the chromogenic N-acylaminonitrophenyl moiety. Phospholipase C preparations do not hydrolyze this compound. The starting material is 2-amino-4-nitrophenol which wh...

journal_title：Chemistry and physics of lipids

authors： Gal AE,Fash FJ

更新日期：1976-02-01 00:00:00